Cuando Prior Walter le confiesa a su amante Lou que ha contraído el SIDA, éste lo abandona. A medida que la enfermedad y la soledad destruyen a Prior, la culpa consume a Lou. Al mismo tiempo, Roy Cohn, un hombre muy influyente, anima a Joe Pitt, un abogado mormón y republicano, a trabajar en el Departamento de Justicia. Ambos ocultan su homosexualidad: Pitt por vergüenza y por razones religiosas, Cohn para conservar el poder. Por su parte, Harper, la frustrada esposa de Pitt, está deseando librarse de la farsa de su matrimonio. Un ángel mensajero invita a Prior a actuar como un profeta.
Millennium Approaches: Bad News (Episodio 1) 7.4
Guionista: Tony Kushner
Fecha de emisión: 2003-12-07
Duración: 66 min
Sinopsis: Prior Walter is diagnosed with AIDS that changes his life and he must deal with such new obstacle. Moreover, his partner abandoned him. He has also increasing hallucinations and Mormon's mother comes to New York in order to save her son's marriage. Meanwhile, Roy Cohn checks into the hospital.
Millennium Approaches: In Vitro (Episodio 2) 8.0
Guionista: Tony Kushner
Fecha de emisión: 2003-12-07
Duración: 55 min
Sinopsis: Louis abandons a hospitalized Prior; Joe and Roy confide in each other over drinks. Later, Prior hears voices from his hospital bed while Louis solicits sex from strangers, and Joe makes a drunken confession to his mother.
Millennium Approaches: The Messenger (Episodio 3) 7.4
Guionista: Tony Kushner
Fecha de emisión: 2003-12-07
Duración: 58 min
Sinopsis: Prior returns home and is visited by a pair of spectral namesake ancestors who herald the arrival of the messenger; a tussle with Joe leaves Roy with the ghost of Ethel Rosenberg. Later, Joe and Louis hook up in Central Park while Prior meets the angelic messenger.
Perestroika: Stop Moving! (Episodio 4) 7.6
Guionista: Tony Kushner
Fecha de emisión: 2003-12-14
Duración: 57 min
Sinopsis: The story continues with Prior finally confronting the visions, Cohn desperately trying to manipulate the system to his benefit - all the while haunted by one of his victims, and Harper attempting to regain control of her life.
Perestroika: Beyond Nelly (Episodio 5) 6.1
Guionista: Tony Kushner
Fecha de emisión: 2003-12-14
Duración: 63 min
Sinopsis: Louis arranges a meeting with Prior; Joe visits Roy in the hospital and gets an unwelcome father's blessing; Prior drags Belize to the courthouse for a surprise meeting with the clerk and later strikes up a friendship with Hannah. High on morphine, Roy paints a different picture of heaven.
Perestroika: Heaven, I'm in Heaven (Episodio 6) 10.0
Guionista: Tony Kushner
Fecha de emisión: 2003-12-14
Duración: 76 min
Sinopsis: A fight with Joe leaves Louis badly scarred; Roy plays a final practical joke on Ethel; Prior wrestles the Angel and then addresses a review board in Heaven; Harper heads out West; Prior, outliving his diagnosis, pays a visit to his favorite angel and vows to keep living--free of secrets.