Drew Barrymore presents human-interest stories, celebrity guests, lifestyle segments and field pieces, all driven by her infectious brand of humor and optimism.
The Drew Barrymore Show (Season 6)
Valerie Bertinelli; Catherine Zeta-Jones (Episode 1)
Air date: 2025-09-08
Overview: Catherine Zeta-Jones joins Drew for the Season 6 premiere to tell her all about the exciting second season of "Wednesday"; Drew covers the headlines with pals Ross Mathews and Valerie Bertinelli.
Halle Berry; Kristina Zias (Episode 2)
Air date: 2025-09-08
Overview: Drew, Halle Berry and Kristina Zias celebrate aging by helping a viewer over 50 achieve a glow-up look.
Halle Berry; Nate Burleson; Valerie Bertinelli; Melani Sanders (Episode 3)
Air date: 2025-09-09
Overview: Halle Berry, Valerie Bertinelli, viral sensation Melani Sanders and Nate Burleson join Drew for a Fearless After 50 roundtable discussion.
Issa Rae (Episode 4)
Air date: 2025-09-09
Overview: Issa Rae tells Drew about her new book, "I Should Be Smarter by Now," and upcoming two-part docuseries, "Seen & Heard."
Valerie Bertinelli; Pilar Valdes (Episode 5)
Air date: 2025-09-10
Overview: Valerie Bertinelli joins Drew and Ross Mathews to hit the headlines; Drew tells a special Adam Sandler story in honor of his birthday; Pilar Valdes has some easy advice for a week of meal prepping.
Michael and Cameron Douglas (Episode 6)
Air date: 2025-09-10
Overview: Drew chats with father-son duo Michael and Cameron Douglas.
David Letterman (Episode 7)
Air date: 2025-09-11
Overview: Drew sits down with David Letterman, who plays a round of memory bank and shares his memories of some of his most iconic moments.
Sunny Anderson (Episode 8)
Air date: 2025-09-11
Overview: Sunny Anderson covers the headlines with Drew and Ross and provides suggestions for decluttering your closet and an easy dip recipe.
Sunny Anderson; Emeril Lagasse (Episode 9)
Air date: 2025-09-12
Overview: Sunny Anderson gets a big surprise from Drew: cooking with the legendary Emeril Lagasse!
Jennifer Aniston (Episode 10)
Air date: 2025-09-12
Overview: Drew chats with Jennifer Aniston about the new season of "The Morning Show," her kids cookbook, "Cook With Clydeo," and her hair care line.
Seasons
Episodes 111
Episodes 86
Episodes 158
Episodes 14
Episodes 15
Episodes 10