An emotional thrill ride through the day-to-day chaos of the city's most explosive hospital and the courageous team of doctors who hold it together. They will tackle unique new cases inspired by topical events, forging fiery relationships in the pulse-pounding pandemonium of the emergency room.
We All Fall Down (Episode 1) 8.8
Writer: Allen MacDonald
Air date: 2025-10-01
Runtime: 43 min
Overview: A family of victims from a house fire is rushed to Gaffney. Lenox fights to save two sisters injured in an all-night rave turned tragedy. Tensions mount between Goodwin and Abrams over difficult staffing changes.
A Game of Inches (Episode 2) 7.0
Writer: Lauren MacKenzie
Air date: 2025-10-08
Runtime: 43 min
Overview: Things get personal when Ripley and Archer butt heads over an unusual case. Asher makes a surprising discovery with an expectant couple. A patient throws the hospital into chaos.
Horseshoes and Hand Grenades (Episode 3) 7.0
Writer: Stephen Hootstein
Air date: 2025-10-15
Runtime: 43 min
Overview: Lenox and Frost receive an unusual request from the parents of a patient on life support. Ripley and Charles work with a man who can't remember who he is.
Found Family (Episode 4) 8.0
Writer: Zoe Cheng
Air date: 2025-10-22
Runtime: 43 min
Overview: Charles races to convince a patient to accept treatment before it's too late. Frost bonds with a young girl battling immunodeficiency. Lenox makes a chilling discovery.
What's Hiding in the Dark (Episode 5) 8.8
Writer: Meridith Friedman
Air date: 2025-10-29
Runtime: 43 min
Overview: A personal clash between Asher and Archer reaches a breaking point. Charles and Ripley uncover a rare neurological disorder in a patient. Goodwin's personal life is put to the test.
The Story of Us (Episode 6) 8.5
Writer: Deanna Shumaker
Air date: 2025-11-05
Runtime: 43 min
Overview: Secrets are uncovered when Goodwin's family comes together for Bert. Ripley and Frost treat two children stung by hornets in a treehouse. A member of the team struggles with relationship woes.
Double Down (Episode 7) 8.5
Writer: Ashley Bower
Air date: 2025-11-12
Runtime: 43 min
Overview: Charles grows increasingly suspicious of a colleague's intentions. Lenox crosses a line to protect a patient. Hannah and Archer treat a soon-to-be father battling cancer.
Triple Threat (Episode 8)
Writer: Stephen Hootstein
Air date: 2026-01-07
Runtime: 43 min
Overview: The doctors deal with the professional and personal fallout from the choices made during a city-wide power outage.
Blindsided (Episode 9) 10.0
Writer: Andrew Gettens
Air date: 2026-01-14
Runtime: 43 min
Overview: Tensions spike when a road rage incident sends three patients into the ED. Frost's former television co-star resurfaces. An unexpected arrival catches Asher and Archer off guard.
Frost on Fire (Episode 10) 10.0
Writer: Meridith Friedman
Air date: 2026-01-21
Runtime: 43 min
Overview: Archer and Frost confront a troubling medical mystery while treating a college basketball player. Lenox's treatment of a surrogate patient leads to unexpected complications for the patient and her best friend.
Our So-Called Lives (Episode 11) 9.8
Writer: Zoe Cheng
Air date: 2026-01-28
Runtime: 43 min
Overview: Old resentment stirs up Charles when his best friends from med school visit. Asher is forced to overcome obstacles in the treatment of one of her patients. Ripley looks to honor his best friend, Sully, on the one-year anniversary of his death.
Spill Your Guts (Episode 12) 10.0
Writer: Conor Patrick Hogan
Air date: 2026-02-04
Runtime: 43 min
Overview: Charles faces a new challenge when three medical students shadow him for a day. Goodwin faces a high-stakes board meeting. Frost reckons with his past.
Episode 13 (II) (Episode 13)
Air date: 2026-03-04
Overview: Firehouse 51 is called to an airfield when a passenger jet suddenly goes silent mid-air, triggering a high-stakes emergency. Their discovery cracks open a bigger and deadlier mystery — one with consequences that could ripple far beyond the runway and put countless lives in jeopardy.
The crossover begins on Chicago Fire S14E13 (I). It continues on Chicago P.D. S13E13 (III).