节目会请一些嘉宾来讨论当前政坛和媒体上的事件。与之前节目不同的是，马赫脱口秀请到的嘉宾往往对所讨论问题有比较充分的认识，嘉宾中演员和名人比较少。另外，很多嘉宾是以卫星连线的形式参与的。节目的长度约为一小时，在摄影棚内有观众现场观看，东部时间每周五晚十点直播。节目源自于洛杉矶CBS电视台的第33摄影棚（“Bob Barker摄影棚”）。春季（二月到五月上旬）约播出12集，秋季（八月下旬到十一月）也播出数量相当的集数。由于节目针对的是时事，所以HBO电视台一般在节目间歇的月份不会安排重播，但偶尔如果有一周节目不播的话，会安排重播之前的节目。
播出日期: 2014-01-17
运行时间: 60 min
概述: Interviewee: Glenn Greenwald Panelists: Steve Schmidt, Jennifer Granholm, James Carville Panel Guest: (a very stoned) Mary Matalin Topics: Obama's speech on NSA reform, Chris Christie's Fort Lee lane closure scandal, Benghazi, Independents' self-identification rising, 2014 Elk River chemical spill, marriage between a Democrat and a Republican, global warming affecting animals, Republicans' war against the poor, unemployment benefits, minimum wage, women in US politics.
播出日期: 2014-01-24
运行时间: 60 min
概述: Interviewee: Erin Brockovich Panelists: Josh Barro, Howard Dean, Carly Fiorina Panel Guest: Willie Nelson Topics: 2014 Elk River chemical spill and coal mining, Republicans and women issues, Obamacare, Richard Sherman's outburst after game against the San Francisco 49ers, Obama's inconsistent policies about marijuana, poverty and income inequality, 2014 Winter Olympics and Vladimir Putin's comments on LGBT people.
播出日期: 2014-01-31
运行时间: 60 min
概述: Interviewee: John Ridley ("12 Years a Slave" screenwriter) Panelists: Chrystia Freeland (Canadian Member of Parliament), Ronan Farrow (MSNBC host), Darrell Issa (R-CA) Panel Guest: Stephen Merchant (writer/actor "Hello Ladies") Topics: Solomon Northup and slavery, 2014 State of the Union Address, minimum wage in the United States, income inequality, demographics of the top 1%, Gerrymandering, differences between UK and US politics, stand-your-ground laws and African Americans, gun politics, Michael Grimm threatening a reporter, Flip a District, puritanism.
播出日期: 2014-02-07
运行时间: 60 min
概述: Interviewee: Charlie Crist Panelists: Tom Colicchio, Alicia Menendez, S. E. Cupp Panel Guest: P. J. O'Rourke Topics: Independents in US politics, Cuban embargo, immigration reform, executive orders, Congressional Budget Office's report on Obamacare's effect on jobs, lowest abortion rates in 30 years, Russia and communism, heroin and prescription drugs, United States Department of State's report on the Keystone Pipeline, federal spending for children vs. for senior citizens.
播出日期: 2014-02-14
运行时间: 60 min
概述: Interviewee: Jeremy Scahill ("Dirty Wars" Docu-maker) Panelists: Andrew Sullivan ("Daily Dish" blogger), Mayim Bialik ("Big Bang Theory" star and vegan author), Eric Klinenberg ("Going Solo" author) Panel Guest: Bill Nye Topics: Creationism vs. science, Comcast–Time Warner Cable merger, net neutrality, drop in infrastructure spending, targeted killings of US citizens who plot against other Americans, veganism, attachment parenting, World Health Organization's warning about cancer, Philip Seymour Hoffman's published diaries, Edward Snowden praising Russia.
播出日期: 2014-02-21
运行时间: 60 min
概述: Interviewee: Michelle Alexander Panelists: Charles Cooke, Jane Harman, Rachel Maddow Panel Guest: Steve Coogan Topics: The New Jim Crow, incarceration in the US, human rights in North Korea, MSNBC's overcoverage of the Chris Christie scandal, BYU's anti-masturbation campaign, Philomena, forced adoptions in the Catholic Church, Pat McCrory blocking lawsuits against Duke Energy, drought in California and regulations, John Kerry's statement about climate change.
播出日期: 2014-02-28
运行时间: 60 min
概述: Interviewee: Christopher Leonard (author "The Meat Racket") Panelists: Austan Goolsbee, Margaret Hoover, William Kristol Panel Guest: Bruce Dern Topics: The Meat industry's secretiveness, Obama's failed efforts to reform corporate agribusiness, azodicarbonamide in Subway bread, Tea Party movement and bailouts, military budget of the United States, intervention vs. diplomacy, poverty in the Midwest, WhatsApp acquired by Facebook, homophobia in the bible, victim playing by the 1 percent.
播出日期: 2014-03-14
运行时间: 60 min
概述: Interviewee: Alan Weisman (author of "Countdown") Panelists: Andrew Sullivan, Salman Rushdie, Amy Chua Panel Guest: Seth MacFarlane Topics: Environmentalism and overpopulation, family planning in Iran, 2014 Crimean crisis, Rand Paul winning the 2014 CPAC straw poll, paid time off in the United States and Europe, Cosmos: A Spacetime Odyssey, Rush Limbaugh's comment on 12 Years a Slave winning the Academy Award for Best Picture, SAT changes for 2016, random religious rules.
播出日期: 2014-03-21
运行时间: 60 min
概述: Interviewee: Errol Morris (author of "The Unknown Known") Panelists: Keith Ellison, Sheila Bair, Simon Schama Panel Guest: Shane Smith (host of Vice) Topics: The Unknown Known, Donald Rumsfeld & the Iraq War, 2014 midterm elections, Democrats & gun politics, Flip a District candidates: Michael Grimm & Blake Farenthold, Greenland & climate change in the Arctic, CNN & quality of journalism in the 24-hour news cycle, 2014 Russian military intervention in Ukraine, relationship between Pakistan & bin Laden.
播出日期: 2014-03-28
运行时间: 60 min
概述: Interviewee: Jimmy Carter (former U.S. President) Panelists: W. Kamau Bell, Neera Tanden, Rick Lazio Panel Guest: Josh Gad Topics: A Call to Action: Women, Religion, Violence, and Power, treatment of women in various countries, militarized police force, GM's recall of vehicles & corporations' liability, Paul Ryan's statements about inner cities compared to Michelle Obama's, Erdoğan banning Twitter and YouTube, Frozen & gay conspiracy theory, Sebelius v. Hobby Lobby, marine pollution.
播出日期: 2014-04-04
运行时间: 60 min
概述: Interviewees: Paul Watson (Captain) Panelists: Alex Wagner (MSNBC host), Tom Davis (R-VA), and Carrie Sheffield (Forbes columnist) Panel Guest: Nas (Hip Hop icon) Topics: Marine pollution, Obamacare reaching its target number of enrollees, Flip a District candidates: Kerry Bentivolio & Scott Garrett, gerrymandering, McCutcheon v. Federal Election Commission & unlimited campaign contributions, 2014 Fort Hood shooting & PTSD, United States Senate Select Committee on Intelligence's report on torture.
播出日期: 2014-04-11
运行时间: 60 min
概述: Interviewees: Maria Alyokhina & Nadezhda Tolokonnikova (members of Pussy Riot) Panelists: Rob Lowe, Duncan D. Hunter, Ana Marie Cox Panel Guest: Matt Taibbi Topics:
播出日期: 2014-04-25
运行时间: 60 min
概述: Interviewee: Tom Steyer (Hedge Fund Manager & Philanthropist) Panelists: John Avlon ("Daily Beast" Editor), Charles Murray ("Curmudgeon" author), and Christine Quinn (Ex-NYC Councilwoman) Panel Guest: Annabelle Gurwitch (Comedian) Topics:
播出日期: 2014-05-02
运行时间: 60 min
概述: Musician Ziggy Marley, Ex-NBA Player Kareem Abdul-Jabbar, Lt. Governor Gavin Newsom (D-CA), "Blood Will Out" Author Walter Kirn, and Financial Consultant Monica Mehta.
播出日期: 2014-05-09
运行时间: 60 min
概述: Interviewee: Sister Simone Campbell ("Nun on a Bus") Panelists: Matt Welch ("Reason" magazine Editor-in-Chief), Baratunde Thurston (Author and Comic), Arianna Huffington ("Thrive" Scribe and HuffPost Founder) Panel Guest: Dinesh D'Souza (Conservative Film-maker) Topics:
播出日期: 2014-05-16
运行时间: 60 min
概述: Comedian and Actor Kevin Nealon, Ex-Governor Brian Schweitzer (D-MN), from "Fed Up" Dr. Robert Lustig, GOP Pollster Kellyanne Conway and Author of "Every Nation for Itself" Ian Bremmer.
播出日期: 2014-05-23
运行时间: 60 min
概述: Jose Antonio Vargas, Anna Deavere Smith, Michael Smerconish, David Frum and Sarah Silverman.
播出日期: 2014-06-06
运行时间: 60 min
概述: John Waters, Anthony Weiner, Ralph E. Reed, Jr., Nicolle Wallace and Jim Geraghty
播出日期: 2014-06-13
运行时间: 60 min
概述: EPA Head Gina McCarthy, MSNBC Co-Host Krystal Ball, Novelist Richard Clarke, Comedian Carol Leifer and Conservative Blogger Tom Rogan.
播出日期: 2014-06-20
运行时间: 60 min
概述: "No Place to Hide" Author Glenn Greenwald, Linkin Park's Michael Shinoda, Atlantic Journalist Ta-Nehisa Coates, I.A.V.A. Founder Paul Rieckhoff, and Conservative Pollster Kristen Soltis.
播出日期: 2014-06-27
运行时间: 60 min
概述: Bill's guests are: Martin Blaser, Max Brooks, Bobby Ghosh, Andy Litinsky, and Joy-Ann Reid.
播出日期: 2014-07-11
运行时间: 60 min
概述: Author Sandra Tsing-Loh, Pulitzer prize-winner Ron Suskind, Rep. Donna Edwards (D-MD), and National Review's Reihan Salam.
播出日期: 2014-07-18
运行时间: 60 min
概述: Rev. Dr. William J. Barber II, president of North Carolina NAACP; actor George Takei; former Rep. Jane Harman (D- Calif.); statistician Nate Silver; editor Jamie Weinstein.
播出日期: 2014-07-25
运行时间: 60 min
概述: "Cosmos" star Neil deGrasse Tyson, Democracy Now's Amy Goodman, Freedomworks' Matt Kibbe, GOP Strategist Hogan Gidley.
播出日期: 2014-08-01
运行时间: 60 min
概述: Political activist Ralph Nader; author Douglas Brinkley; deputy chief of staff to the House Majority Leader, Doug Heye; Rep. Barbara Lee (D-Calif.).
播出日期: 2014-09-12
运行时间: 60 min
概述: Live from Washington D.C. Guests include comedy legend Jerry Seinfeld, Ex-Speaker of the House Nancy Pelosi (D-CA) followed by a live stand-up special.
播出日期: 2014-09-19
运行时间: 60 min
概述: Former Secretary of State Gen. Colin Powell; political activist Matthew Segal; Rep. Jack Kingston (R-Ga.); editor Katrina vanden Heuvel; actor Wendell Pierce.
播出日期: 2014-09-26
运行时间: 60 min
概述: Social activist Naomi Klein; filmmaker Alexandra Pelosi; journalist Charles M. Blow; journalist John Feehery; Gen. Anthony Zinni.
播出日期: 2014-10-03
运行时间: 60 min
概述: This weeks guests include Oscar winner Ben Affleck, Senator Elizabeth Warren (D-MA), New York Times Op-Editor Nicholas Kristoff, Ex-RNC Chair Michael Steele, and "Waking Up" author Sam Harris.
播出日期: 2014-10-17
运行时间: 60 min
概述: This weeks guests include Senator Kirsten Gillibrand (D-NY), Representative Barbara Lee (D-CA), Ex-British Foreign Secretary David Miliband, and "Atlantic" Senior Editor David Frum.
播出日期: 2014-10-24
运行时间: 60 min
概述: "Black Prophetic Fire" Author Cornel West, Conservative Commentator Mary Matalin, "Daily Beast" Editor-In-Chief John Avlon.
播出日期: 2014-10-31
运行时间: 60 min
概述: Actress and "Food Chain" EP Eva Longoria, Author and General (Ret.) Wesley Clark, Senator Angus King (I-ME), and Journalist Rula Jebreal.
播出日期: 2014-11-07
运行时间: 60 min
概述: Senator Bernie Sanders (I-VT), "Comeback" star Lisa Kudrow, Washington Post's Robert Costa, Daily Beast's Kristen Soltis Anderson.
播出日期: 2014-11-14
运行时间: 60 min
概述: Rep. Rand Paul (R-KY), Comedy Legend Martin Short, Founding Editor of "The Dish" Andrew Sullivan, CNN Political Contributor Margaret Hoover, and Investigative Journalist Jeremy Scahill.
播出日期: 2014-11-21
运行时间: 60 min
概述: Season Finale. "The Interview" star Seth Rogen, MSNBC "Hardball" host Chris Matthews, Monty Python Alum & "So Anyway..." author John Cleese, Canadian MP Chrystia Freeland and "News One Now" host Roland Martin.
