Inspector Lewis Erskine (Efrem Zimbalist jr.), ein ernster, ehrlicher und ruhiger Mann, ermittelt für das Federal Bureau of Investigation (FBI) in kniffligsten Fällen aus verschiedensten Verbrechenssparten. Bei der Jagd nach Drogendealern, Entführern, Mördern und Geldfälschern unterstützen ihn die Agenten Arthur Ward (Philip Abbott), Jim Rhodes (Stephen Brooks) und Tom Colby (William Reynolds) sowie Chris Daniels (Shelly Novack). Rhodes ist gleichzeitig der Freund von Erskines Tochter Barbara (Lynn Loring). Dankbar nimmt die Welt die Arbeit der höflichen Beamten an.Die Fälle basierten auf tatsächlichen Fällen des FBI.
F.B.I. (Staffel 1)

The Monster (Folge 1)
Sendedatum: 1965-09-19
Laufzeit: 60 min
Übersicht: Case file #76-3342-J- Francis Jerome - Escaped Federal Prisoner.
Image in a Cracked Mirror (Folge 2)
Sendedatum: 1965-09-26
Laufzeit: 60 min
Übersicht: Case file #29-68954-G - Charles Emery Gates - Federal Reserve Act, Embezzlement.
A Mouthful of Dust (Folge 3)
Sendedatum: 1965-10-03
Laufzeit: 60 min
Übersicht: Case file #70-68307-C - Joseph Cloud - Crime on Indian Reservation.
Slow March Up a Steep Hill (Folge 4)
Autor: Charles Larson
Sendedatum: 1965-10-10
Laufzeit: 60 min
Übersicht: Case file #91-77270-X - Wayne Everett Powell - Bank Robbery, Interstate Transportation of Stolen Motor Vehicle.
The Insolents (Folge 5)
Sendedatum: 1965-10-17
Laufzeit: 60 min
Übersicht: Case file #45-47339-Y - Roger York - Crime on the High Seas - Murder.
To Free My Enemy (Folge 6)
Sendedatum: 1965-10-24
Laufzeit: 60 min
Übersicht: The good inspector has the distasteful job of finding a kidnap victim--a pornographer that the good inspector is trying build a case against. In the end, Erskine captures the kidnappers and obtains a warrant for the arrest of the pornographer.
The Problem of the Honorable Wife (Folge 7)
Sendedatum: 1965-10-31
Laufzeit: 60 min
Übersicht: Case file #98-63520-M - Maury Maddock - Sabotage.
Courage of a Conviction (Folge 8)
Autor: Oscar Millard
Sendedatum: 1965-11-07
Laufzeit: 60 min
Übersicht: Case file #87-633462-C - Harry Castle - Interstate Transportation of Stolen Property, Fraudulent Checks.
The Exiles (Folge 9)
Autor: Robert Leslie Bellem
Sendedatum: 1965-11-14
Laufzeit: 60 min
Übersicht: Case file #2-46675-R - General Romero, et al. - Violation of Neutrality Act.
The Giant Killer (Folge 10)
Sendedatum: 1965-11-21
Laufzeit: 60 min
Übersicht: Case file #52-19223-W - Joseph Maurice Walker - Destruction of Government Property.

All the Streets Are Silent (Folge 11)
Sendedatum: 1965-11-28
Laufzeit: 60 min
Übersicht: Case file #52-499362-M - Mike Murtaugh - Theft of Government Property.
An Elephant is Like a Rope (Folge 12)
Autor: Robert Leslie Bellem
Sendedatum: 1965-12-05
Laufzeit: 60 min
Übersicht: Case file #87-52739-X - John Doe - Interstate Transsportation of Stolen Property. $500,000 that nobody would claim, and a man who has lost his memory are Inspector Erskine's and Agent Jim Rhodes' only lead to a crime within a crime.

How to Murder an Iron Horse (Folge 13)
Autor: Don Brinkley
Sendedatum: 1965-12-12
Laufzeit: 60 min
Übersicht: Case File #9-74219-C - Howard Spencer Collier Jr. - Extortion. Inspector Lew Erskine and Special Agent Jim Rhodes hunt a young man involved with railroad sabotage.
Pound of Flesh (Folge 14)
Sendedatum: 1965-12-19
Laufzeit: 60 min
Übersicht: The FBI Investigates the murder of an Army Chaplains wife on an U.S. Army base.
The Hijackers (Folge 15)
Autor: Norman Lessing
Sendedatum: 1965-12-26
Laufzeit: 60 min
Übersicht: Case file #15-9436-S - Harold K. Smith - Theft from Interstate Shipment.
The Forests of the Night (Folge 16)
Autor: Charles Larson
Sendedatum: 1966-01-02
Laufzeit: 60 min
Übersicht: Case file #9-26080-X Adam MacDonald, et al., Victims - Extortion.

The Chameleon (Folge 17)
Sendedatum: 1966-01-09
Laufzeit: 60 min
Übersicht: Case file #29-31091-C - Andrew S. Cook, Jr., with Aliases - Violation of Federal Reserve Act, Interstate Transportation of Stolen Property, Murder. A clever confidence man of a thousand faces plays a deadly game of cat & mouse with a million dollars as the prize

The Sacrifice (Folge 18)
Sendedatum: 1966-01-16
Laufzeit: 60 min
Übersicht: Case file #65-9525-X - The Doriskin Papers - Espionage. Inspector Lew Erskine infiltrates a spy network and is marked for assassination.
Special Delivery (Folge 19)
Sendedatum: 1966-01-23
Laufzeit: 60 min
Übersicht: Case file #91-42238-P - Robert Charles Porter - Bank Robbery, Unlawful Flight, Murder. Inspector Erskine goes undercover to crack an inter-hemisphere fugitive smuggling ring.
Quantico (Folge 20)
Autor: Don Brinkley
Sendedatum: 1966-01-30
Laufzeit: 60 min
Übersicht: Case File #52-7672-S - Willard Smith - Destruction of Government Property. A plot to destroy The Supreme Court Building could cost an F.B.I. agent his job.

The Spy Master (Folge 21)
Sendedatum: 1966-02-06
Laufzeit: 60 min
Übersicht: Case file #65-4948-X - The Forsythe Memo - Espionage. Inspector Lew Erskine masquerades as a traitor to break up a Red Chinese spy operation.
The Baby Sitter (Folge 22)
Sendedatum: 1966-02-13
Laufzeit: 60 min
Übersicht: Case file #7-1101-D - Mrs. Amy Doucette - Kidnapping. Lew Erskine leads a three state search for a deranged woman who kidnaps an infant she has been baby-sitting.

Flight to Harbin (Folge 23)
Autor: Charles Larson
Sendedatum: 1966-02-27
Laufzeit: 60 min
Übersicht: Case file #164-4391-K - Charles Wallace King - Alias Ernest C. Putnam - Crime Aboard Aircraft - Piracy - Attempted Murder. Inspector Erskine must save the lives of airline passengers aboard a flying prison of terror.
The Man Who Went Mad by Mistake (Folge 24)
Autor: Robert Leslie Bellem
Sendedatum: 1966-03-06
Laufzeit: 60 min
Übersicht: Case file #115-28414-T - Mark Stephen Tabor - Bond Default, Fraud Against The Government, Unlawful Flight.
The Divided Man (Folge 25)
Sendedatum: 1966-03-20
Laufzeit: 60 min
Übersicht: Case file #98-81829-M - Roger Leroy Mason - Sabotage.
The Defector (1) (Folge 26)
Autor: Norman Lessing
Sendedatum: 1966-03-27
Laufzeit: 60 min
Übersicht: Case file #65-22317-H - The Holman Defection - Espionage. The F.B.I. seeks to protect the life of an Eastern European cryptographer who defects to the United States.
The Defector (2) (Folge 27)
Autor: Norman Lessing
Sendedatum: 1966-04-03
Laufzeit: 60 min
Übersicht: Case file #65-22317-H - The Holman Defection - Espionage. The F.B.I. plays a deadly game of espionage with foreign assassins who seek the life of an Eastern European defector to the U.S.
The Tormentors (Folge 28)
Sendedatum: 1966-04-10
Laufzeit: 60 min
Übersicht: Case file #7-4929-D - Logan Clyde Dupree, John Carl Brock, Anita James - Kidnapping. A desperate father jeopardizes the life of his kidnapped son when he defies F.B.I. warnings to keep the story out of the media.
The Animal (Folge 29)
Sendedatum: 1966-04-17
Laufzeit: 60 min
Übersicht: Case file #76-2947-C - Earl Clayton, Roy Joe Spencer, et al. - Escaped Federal Prisoners, Killing a Federal Officer.
The Plunderers (Folge 30)
Sendedatum: 1966-04-24
Laufzeit: 60 min
Übersicht: Case file #91-62290-H - King Hogan, Frank Donald Collins, Otto Hans Breese, Edward Ralph Richards - Bank Robbery, Murder. The F.B.I. leads a search for bank robbers who did not take enough money.
The Bomb That Walked Like a Man (Folge 31)
Autor: Charles Larson
Sendedatum: 1966-05-01
Laufzeit: 60 min
Übersicht: Case file #7-76881-H - Dale Vernon Hillman - Kidnapping, Murder. Inspector Lew Erskine seeks a kidnapper-killer who tries to hide in a para-military hate group.
The Hiding Place (Folge 32)
Sendedatum: 1966-05-08
Laufzeit: 60 min
Übersicht: Erskine and Rhodes are sent to a small town in Oregon with a predominant Asian American population. Evidence has surfaced that one of its residents may have been a traitor during World War II, serving as a Japanese officer without ever renouncing his U.S. citizenship. The one-time officer also was involved in torture during the war. To find the man, the agents eventually must seek the aid of one of the torture victims from the war.
