El primer cohete espacial británico ha despegado con éxito, y vuelve a la Tierra, pero la comunicación se corta. Sólo uno de los tres astronautas permanece a bordo, y su salud, tanto física como mental está gravemente dañada. Es puesto bajo observación pero su esposa le saca del hospital, liberando de este una gran amenaza para la humanidad, ya que el sobreviviente está siendo consumido por una fuerza alienígena
El Experimento del Doctor Quatermass (Temporada 1)

Contact Has Been Established (Episodio 1)
Fecha de emisión: 1953-07-18
Duración: 30 min
Sinopsis: A British experimental rocket orbits the Earth. After being out of contact for 57 hours, the capsule crashes back to Earth in Wimbledon, London. When the capsule is opened, only one member of the three-man crew emerges, Victor Carroon.

Persons Reported Missing (Episodio 2)
Fecha de emisión: 1953-07-25
Duración: 30 min
Sinopsis: Victor Carroon is subjected to various tests which indicate that he has taken on the identities of the other two men. Quatermass and Paterson find a gelatinous substance spread around the capsule's interior.
Very Special Knowledge (Episodio 3)
Fecha de emisión: 1953-08-01
Duración: 30 min
Sinopsis: Carron is taken back to the crash site and a recording of what happened during the orbit is played back to him, with disturbing results. A group of journalists try to kidnap him, but he, in turn, attacks one of them as he begins to change.
Believed to be Suffering (Episodio 4)
Fecha de emisión: 1953-08-08
Duración: 30 min
Sinopsis: Carroon takes refuge inside a cinema (where a spoof film 'Planet of the Dragons', is on screen). He then goes to a chemist where he appears to in pain and his hand is seen to be badly mutated.
An Unidentified Species (Episodio 5)
Fecha de emisión: 1953-08-15
Duración: 30 min
Sinopsis: Quatermass picks up Carroon's trail and believes that the mixture of chemicals he has taken will accelerate his metamorphosis. Meanwhile, the killing starts - and Westminster Abbey a pulsating mass is revealed clinging to the building.
State of Emergency (Episodio 6)
Fecha de emisión: 1953-08-22
Duración: 30 min
Sinopsis: A state of emergency is declared and the army is brought in. Quatermass plays the creature the rocket tapes and appeals to the last vestiges of humanity left in Carroon to fight what he has become. The creature finally dies, just before it is due to spore.

Temporadas
Episodios 6